Hippocampal atrophy correlates with the severity of cognitive decline

DOĞU B. B., Ariogul S., CANKURTARAN M., Oguz K. K., HALİL M. G., Dagli N., ...More

INTERNATIONAL PSYCHOGERIATRICS, vol.19, no.4, pp.767-777, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1017/s1041610206004303
  • Journal Name: INTERNATIONAL PSYCHOGERIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.767-777
  • Keywords: Alzheimer's disease, mild cognitive impairment, hippocampus, magnetic resonance imaging, Clock Drawing Test, neuroimaging, ALZHEIMERS-DISEASE, ENTORHINAL CORTEX, EARLY-DIAGNOSIS, SPATIAL MEMORY, BRAIN ATROPHY, IMPAIRMENT, DEMENTIA, AD, PROGRESSION, VOLUMES
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: The aim of this study is to compare the results of magnetic resonance (MR) imaging, particularly the decline in hippocampal volume, of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) with healthy age-matched controls, to examine the reliability of hippocampal volumetry in the early diagnosis of AD and the correlation of the severity of hippocampal atrophy with the severity of cognitive decline.