Hippocampal atrophy correlates with the severity of cognitive decline

DOĞU B. B., Ariogul S., CANKURTARAN M., Oguz K. K., HALİL M. G., Dagli N., ...Daha Fazla

INTERNATIONAL PSYCHOGERIATRICS, cilt.19, sa.4, ss.767-777, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1017/s1041610206004303
  • Dergi Adı: INTERNATIONAL PSYCHOGERIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.767-777
  • Anahtar Kelimeler: Alzheimer's disease, mild cognitive impairment, hippocampus, magnetic resonance imaging, Clock Drawing Test, neuroimaging, ALZHEIMERS-DISEASE, ENTORHINAL CORTEX, EARLY-DIAGNOSIS, SPATIAL MEMORY, BRAIN ATROPHY, IMPAIRMENT, DEMENTIA, AD, PROGRESSION, VOLUMES
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: The aim of this study is to compare the results of magnetic resonance (MR) imaging, particularly the decline in hippocampal volume, of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) with healthy age-matched controls, to examine the reliability of hippocampal volumetry in the early diagnosis of AD and the correlation of the severity of hippocampal atrophy with the severity of cognitive decline.