Protective effect of heparin in the end organ ischemia/reperfusion injury of the lungs and heart

Gedik, Hikmet; Korkmaz, Kemal; Erdem, Havva; Karakilic, MUHAMMED; Lafci, Gokhan; ANKARALI, HANDAN

doi:10.1186/1749-8090-7-123

Protective effect of heparin in the end organ ischemia/reperfusion injury of the lungs and heart

Gedik H. S., Korkmaz K., Erdem H., Karakilic E., Lafci G., ANKARALI H.

JOURNAL OF CARDIOTHORACIC SURGERY, vol.7, 2012 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 7
Publication Date: 2012
Doi Number: 10.1186/1749-8090-7-123
Journal Name: JOURNAL OF CARDIOTHORACIC SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Eskisehir Osmangazi University Affiliated: No

Abstract

Background: Ischemia/reperfusion (I/R) injury is harmful to the cardiovascular system and is responsible for the inflammatory response and multiple organ dysfunctions. In this study we investigated the effect of activated clotting time level on the aortic cross-clamping triggers a systemic inflammatory response and it effects to lungs and heart.