Reduced anaerobic and aerobic performance in children with primary ciliary dyskinesia

Simsek S., Inal-Ince D., Çakmak A., Emiralioğlu N., Calik-Kutukcu E., Sağlam M., ...Daha Fazla

EUROPEAN JOURNAL OF PEDIATRICS, cilt.177, ss.765-773, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 177
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00431-018-3121-2
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.765-773
  • Anahtar Kelimeler: Primary ciliary dyskinesia, Pulmonary function test, Children, Exercise test, Muscle strength, ADULT CYSTIC-FIBROSIS, MODIFIED SHUTTLE TEST, PRESCHOOL-CHILDREN, PULMONARY-FUNCTION, REFERENCE VALUES, CEREBRAL-PALSY, EXERCISE, CAPACITY, STRENGTH, WEIGHT
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Primary ciliary dyskinesia (PCD) restricts lifestyle and increases morbidity. The aim of the study was to investigate anaerobic and aerobic performance in children with PCD and their healthy counterparts. Thirty-one children with PCD and 29 age- and sex-matched healthy subjects were studied. Pulmonary function, hand grip strength (HGS), quadriceps strength (QMS), physical activity, anaerobic capacity (muscle power sprint test), and aerobic performance (modified shuttle walk test (MSWT)) were determined. Pulmonary function, HGS, QMS, mean anaerobic power (MAP), and MSWT distance in PCD were significantly lower than those of healthy subjects (p < 0.05). In PCD, the MAP was significantly correlated with age, FEV1, and the mean kcal for 3 days (p < 0.05), and age was its independent predictor (p < 0.05). The MSWT distance was significantly related to gender and weight (p < 0.05), and gender was selected as its independent predictor (p < 0.05). In healthy controls, the MAP was significantly associated with age, gender, FVC, FEV1, HGS, QMS, and the mean kcal for three days (p < 0.05). The MSWT distance was significantly related to weight and body mass index in healthy group (p < 0.05).