Immunotherapy in all aspects

Hanci D., Sahin E., MULUK N. B., CİNGİ C.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, vol.273, no.6, pp.1347-1355, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 273 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1007/s00405-015-3553-5
  • Journal Name: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1347-1355
  • Keywords: Immunotherapy, Subcutaneous immunotherapy (SCIT), Sublingual immunotherapy (SLIT), Effectiveness, Safety, GRASS-POLLEN IMMUNOTHERAPY, ALLERGEN-SPECIFIC IMMUNOTHERAPY, HOUSE-DUST MITE, SUBLINGUAL-SWALLOW IMMUNOTHERAPY, TERM CLINICAL-EFFICACY, T-REGULATORY CELLS, DOUBLE-BLIND, MESSENGER-RNA, FOLLOW-UP, DERMATOPHAGOIDES-PTERONYSSINUS
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Allergen immunotherapy is a form of long-term treatment that decreases symptoms for many people with allergic rhinitis, allergic asthma, conjunctivitis (eye allergy) or stinging insect allergy. In this review, we presented the important topics in immunotherapy. The important aspects of immunotherapy are considered to be "ImmunologA +/- cal responses to immunotherapy"; "The principal types of immunotherapy"; "Effectiveness"; "Indications"; "Contraindications"; "Allergen immunotherapy in children"; "Safety"; and "Anaphylactic reactions after immunotherapy". The principal types of immunotherapy are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy. Both of them can be used in indicated cases. When using SCIT, physicians must be more careful because of reported rare fatal cases. The risks and benefits of continuing allergen immunotherapy in patients who have experienced severe systemic reactions should be carefully considered.