Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats

Onem, G; Aral, E; Enli, Y; Oguz, EO; Coskun, E; Aybek, H; Ozcan, AV; Sacar, M; Bir, LS; Baltalarli, A; Baycu, C

doi:10.1016/j.jss.2005.12.017

Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats

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Onem G., Aral E., Enli Y., Oguz E., Coskun E., Aybek H., ...More

JOURNAL OF SURGICAL RESEARCH, vol.131, no.1, pp.124-130, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 131 Issue: 1
Publication Date: 2006
Doi Number: 10.1016/j.jss.2005.12.017
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.124-130
Eskisehir Osmangazi University Affiliated: No

Abstract

Background. Neurological injury because of transient cerebral ischemia is a potential complication of cardiovascular surgery. In this study, the neuroprotective effects of L-carnitine, vitamin E, and the combination of these agents on ischemia/reperfusion (I/R) injury were determined in a rat model of transient global cerebral I/R.