Cerebral palsy due to nonlethal maternal carbon monoxide intoxication

Alehan F., Erol I., Onay Ö.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, vol.79, no.8, pp.614-616, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 79 Issue: 8
  • Publication Date: 2007
  • Doi Number: 10.1002/bdra.20379
  • Journal Name: BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.614-616
  • Keywords: fetal brain damage, CO intoxication, cerebral palsy, PREGNANCY, PATHOGENESIS
  • Eskisehir Osmangazi University Affiliated: No

Abstract

BACKGROUND: Carbon monoxide (CO) poisoning in pregnancy is a relatively rare occurrence, but it can result in fetal mortality and neurologic complications in fetuses who survive to term. CASE: We describe the course of an infant who was acutely exposed to CO at 20 weeks of gestation. CONCLUSIONS: We conclude that despite maternal well-being, CO intoxication at critical periods of human brain development can lead to hypoxic-ischemic lesions in the globus pallidus and that dystonic cerebral palsy may develop in the infant during long-term follow-up.