LIFE SCIENCES, vol.246, 2020 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
Diabetes, Liver, Sonic hedgehog, Endoplasmic reticulum stress, OXIDATIVE STRESS, ANTIOXIDANT STATUS, SIGNALING PATHWAY, CELL FUNCTION, ER STRESS, EXPRESSION, MELLITUS, HYPERGLYCEMIA, ACTIVATION, MECHANISMS
Eskisehir Osmangazi University Affiliated:
Aims: Diabetes is a common metabolic disease which damages many organs including the liver and causes endoplasmic reticulum (ER) stress, which originates from non-folded proteins. Sonic hedgehog (Shh) pathway plays a role in liver regeneration and repair. To our knowledge, there is no study showing the relation between ER stress and Shh pathway in the liver in diabetes. Thus, the aim of this study was to investigate the interaction between ER stress and Shh pathway in the liver of diabetic mice.