Comparison of serum human Klotho levels and thiol/disulfide homeostasis in women with polycystic ovary syndrome and in healthy women

BIYIK İ., ULAŞ Ö., Isiklar Ö. Ö. , İNCE O., SOYSAL C., BERİKTEN D., ...More

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, vol.60, no.3, pp.487-491, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1016/j.tjog.2021.03.017
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.487-491
  • Keywords: PCOS, Klotho, Native thiol, Cardiometabolic risk, Thiol, disulfide homeostasis, LIPID-ACCUMULATION PRODUCT, METABOLIC SYNDROME, INDEX, RISK, ASSOCIATION, PHENOTYPES, PREDICTOR, MARKER, GENE
  • Eskisehir Osmangazi University Affiliated: No


Objectives: Women with polycystic ovary syndrome (PCOS) have an increased cardiometabolic risk. Similarly, it was previously shown that atherosclerotic and cardiovascular risk is increased in the general population with lower serum Klotho levels. The aim of this study was to investigate the lotho and thiol/ disulfide levels in women with non-obese PCOS compared to healthy controls and also to investigate the relationship of serum Klotho and thiol/disulfide homeostasis with cardiometabolic risk factors.