Does the urinary excretion of alpha 1-microglobulin and albumin predict clinical disease activity in ulcerative colitis?


DERİCİ Ü., Tuncer C., Ebinc F. A., Mutluay R., Yakaryilmaz F., Kulaksizoglu S., ...More

ADVANCES IN THERAPY, vol.25, no.12, pp.1342-1352, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 12
  • Publication Date: 2008
  • Doi Number: 10.1007/s12325-008-0109-8
  • Journal Name: ADVANCES IN THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1342-1352
  • Eskisehir Osmangazi University Affiliated: No

Abstract

There remains some difficulty in determining disease activity during the development of inflammatory bowel disease (IBD). The excretion levels of some inflammatory response molecules increase as a result of the onset of this disease. We studied urinary alfa-1-microglobulin (alpha 1-MG) and albumin levels in patients with active and inactive ulcerative colitis (UC) and investigated whether we could use these parameters as an activity index.