Microbial Hydroxylation of S-(-)-Perillyl Alcohol by Fusarium heterosporium
NATURAL PRODUCT COMMUNICATIONS, vol.6, no.12, pp.1805-1806, 2011 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 6 Issue: 12
- Publication Date: 2011
- Doi Number: 10.1177/1934578x1100601203
- Journal Name: NATURAL PRODUCT COMMUNICATIONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1805-1806
- Open Archive Collection: AVESIS Open Access Collection
- Eskisehir Osmangazi University Affiliated: Yes
Abstract
S-(-)-Perillyl alcohol (p-mentha-1, 8-diene-7-ol) (1) (500 mg) was converted by Fusarium heterosporium ATCC 15625 over 10 days at 25 degrees C to a new metabolite, 1,2-dihydroxyperillyl alcohol (p-mentha-8-en-1,2,7-triol) (3) in a yield of 13% (70 mg). The structure of 3 was established by IR and NMR spectroscopic, specific rotation, and mass spectral studies.