Microbial Hydroxylation of S-(-)-Perillyl Alcohol by Fusarium heterosporium

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KIRAN İ.

NATURAL PRODUCT COMMUNICATIONS, vol.6, no.12, pp.1805-1806, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 12
  • Publication Date: 2011
  • Doi Number: 10.1177/1934578x1100601203
  • Journal Name: NATURAL PRODUCT COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1805-1806
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

S-(-)-Perillyl alcohol (p-mentha-1, 8-diene-7-ol) (1) (500 mg) was converted by Fusarium heterosporium ATCC 15625 over 10 days at 25 degrees C to a new metabolite, 1,2-dihydroxyperillyl alcohol (p-mentha-8-en-1,2,7-triol) (3) in a yield of 13% (70 mg). The structure of 3 was established by IR and NMR spectroscopic, specific rotation, and mass spectral studies.