The effects of pentoxifylline on the myocardial inflammation and ischemia-reperfusion injury during cardiopulmonary bypass


Ustunsoy H., Sivrikoz M., Tarakcioglu M., Bakir K., Guldur E., Celkan M.

JOURNAL OF CARDIAC SURGERY, cilt.21, sa.1, ss.57-61, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1540-8191.2006.00169.x
  • Dergi Adı: JOURNAL OF CARDIAC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.57-61
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background: Pentoxifylline (Ptx) decreases necessity of cell energy and inflammatory reactions via inhibition of 5 '-nucleotidase (5 '-NT). The aim of this study is to investigate whether the addition of Ptx into the cardioplegic solutions avoids myocardial inflammatory reactions and ischemia/reperfusion (I/R) injury during extracorpereal circulation.