The effects of pentoxifylline on the myocardial inflammation and ischemia-reperfusion injury during cardiopulmonary bypass

Ustunsoy H., Sivrikoz M., Tarakcioglu M., Bakir K., Guldur E., Celkan M.

JOURNAL OF CARDIAC SURGERY, vol.21, no.1, pp.57-61, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1540-8191.2006.00169.x
  • Journal Name: JOURNAL OF CARDIAC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.57-61
  • Eskisehir Osmangazi University Affiliated: No

Abstract

Background: Pentoxifylline (Ptx) decreases necessity of cell energy and inflammatory reactions via inhibition of 5 '-nucleotidase (5 '-NT). The aim of this study is to investigate whether the addition of Ptx into the cardioplegic solutions avoids myocardial inflammatory reactions and ischemia/reperfusion (I/R) injury during extracorpereal circulation.