Primary unknown solitary brain metastasis: brain recurrence alone


Bayir Angin G., SAYNAK M., KOÇAK Z., ÖZEN A., Alas R. C., Caloglu V. Y., ...Daha Fazla

TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY, cilt.22, sa.2, ss.82-87, 2007 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 2
  • Basım Tarihi: 2007
  • Dergi Adı: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.82-87
  • Anahtar Kelimeler: Solitary brain metastasis, surgery, radiosurgery, unknown primary tumour, whole brain radiotherapy
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

A 53-year-old male patient presented with complaints of headache and paresis in left arm. Cranial computerized tomography and magnetic resonance imaging (MRI) demonstrated a mass in the right parietal region. The solitary tumor was removed by craniotomy. Histological examination showed that it was a squamous cell carcinoma metastasis. The patient subsequently underwent whole brain radiotherapy for a total dose of 30 Gy in 10 fractions and conventional external-beam boost irradiation of 10 Gy in 5 fractions to the tumor margins. He remained disease free until 23 months later. He returned to our clinic with left arm paresis after 24 months. In the left parietal lobe a new lesion was determined on his MRI scan. Partial brain reirradiation at a dose of 25 Gy in 10 fractions was performed. There was a partial regression of symptoms after radiotherapy. In the light of this patient, we reviewed the literature and discussed the treatment strategies of patients with solitary brainmetastasis.