Akademik Veri Yönetim Sistemi
Anestezi Dergisi, cilt.12, sa.2, ss.124-128, 2004 (Scopus)
We compared, hemodynamic responses and recovery properties after either total intravenous anesthesia with remifentanil and propofol or sevoflurane and nitrous oxide in 30 pediatric outpatients. After premedication with midazolam, anesthesia induction was performed with 5-8 % sevoflurane in 50 % nitrous oxide and oxygen in all patients. Patients were randomly assigned to one of the two study groups. For maintainence of anesthesia, sevofluran 3-4 % and N2O was administered in Group I and, remifentanil 0.5 μg kg-1min-1 and propofol 3 mg kg-1hr-1 was administered in Group II. Atracurium 0,25 mg kg-1 was administered for neuromuscular blockade. Heart rate (HR), systolic and diastolic blood pressures (SBP, DBP) and oxyhemoglobin saturation (SpO2) were recorded before anesthesia induction, during surgery and recovery periods. Postoperative recovery characteristics were assesed using Aldrete Recovery Score. Heart rate increased significantly after induction of anesthesia in Group I whereas, significant decreases in HR were observed in Group II after induction and during operation (p<0.05).The systolic and diastolic blood pressures and SpO2 remained unchanged in both groups (p>0.05). There were no significant differences between the groups according to the time of extubation, time of eye opening and Aldrete score. There were no significant differences between the two groups in terms of HR, SBP, DBP and SpO2 during the recovery period. As a conclusion, we observed changes in heart rate during total intravenous anesthesia and inhalation anesthesia with sevoflurane and nitrous oxide, without any change in other hemodynamic parameters. The recovery profiles after anesthesia with remifentanil and propofol appear to be similar to those of sevoflurane and nitrous oxide.