JOURNAL OF COSMETIC DERMATOLOGY, vol.19, no.12, pp.3403-3407, 2020 (SCI-Expanded)
Background Hair graying is a natural process in aging and is not usually associated with a medical problem. It sometimes may occur at early age and is called premature hair graying (PHG). Pathogenesis of PHG is not clear but it was associated with various systemic diseases such as coronary artery diseases, osteopenia, and hypothyroidism.