Akademik Veri Yönetim Sistemi
39th Annual Meeting of the European Society of Paediatric Infectious Diseases (ESPID), 24 - 29 Mayıs 2021, sa.505, ss.827-828
Background: DiGeorge syndrome is characterized as medical problems commonly associated with 22q11.2 deletion syndrome include heart defects, poor immune system function, a cleft palate, and delayed development with behavioral and emotional problems. Although it is uncommon, pediatric brain abscess remains a serious, life-threatening problem. Those with congenital heart disease, an ongoing infection, or an immunocompromised state are particularly at risk.
Case Presentation Summary:A four-year-old boy diagnosed with Di George syndrome, who has multiple cardiovascular anomalies and immune deficiency (take intravenous immunoglobulin treatment because of low serum immunoglobulin levels) patient brought with fever and headache. First laboratory test, hemoglobin 13.3 g/dL, leukocyte 16.300/mm3 (neutrophil 13.500/mm3 , lymphocyte 1200/mm3 ), platelet 201.000/mm3 , C-reactive protein 104 mg/L, erythrocyte sedimentation rate 48 mm/h, procalcitonin 0,3 ng/mL. There are no pathological signs except for flexor spasticity in bilateral lower extremities and tonsillar erythema and enlargement. Because of unknown origin fever, lumbal punction was planned and before the process, a cranial computer tomography was done. In tomography, a huge hypointensity lesion is seen in the frontal brain lobe and cranial MRI was planned, and supratentorial 5.5 x5.5x5 cm lesion was seen on frontal brain lobe, and around of lesions, vasogenic edema was seen. In T2A imaging hyperintensity, in T1A imaging low intensity thought abscess. The abscess was drained, aerobic and anaerobic culture samples were taken from the abscess content. Vancomycin, cefotaxime, and metronidazole treatment were given. Streptococcus constellatus was detected abscesses culture.
Learning Points/Discussion: Early diagnosis, reasonable surgical intervention, and adequate duration
of treatment with effective antibiotics are critical for treating brain abscesses, especially in
immunocompromised patients.