Evaluation of Sella Turcica Shape and Dimensions in Cleft Subjects Using Cone-Beam Computed Tomography


Yasa Y., BAYRAKDAR İ. Ş. , OCAK A., DUMAN Ş. B. , DEDEOĞLU N.

MEDICAL PRINCIPLES AND PRACTICE, vol.26, no.3, pp.280-285, 2017 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1159/000453526
  • Journal Name: MEDICAL PRINCIPLES AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.280-285
  • Keywords: Cleft lip and palate, Morphology, Sella turcica, Cone-beam computed tomography, PITUITARY-GLAND, POSTNATAL SIZE, MORPHOLOGY, LIP, HEIGHT, ABNORMALITIES, GROWTH, PALATE, CT

Abstract

Objective: The aim of this study was to assess the morphology of the sella turcica and measure its size in cleft and noncleft subjects. Material and Methods: Cone-beam computed tomography (CBCT) images of 54 individuals (29 males; 25 females) with cleft and 85 (22 males; 63 females) without cleft were used for this study. Syndromic patients with cleft(s) were not included because of possible additional endocrinological and/or morphological disorders. Linear measurements included length, depth, and diameter. The shape of the sella turcica was analyzed in the cleft and noncleft groups. An independent t test was conducted to evaluate differences between genders and groups. One-way ANOVA was used to compare age groups. Results: The length (p < 0.001) of the sella turcica was smaller in noncleft subjects than in cleft subjects. Diameter (p = 0.014) and depth (p = 0.005) showed as constantly increasing from an age < 15 to >25 years in the overall assessment. The distribution of the shape of the sella turcica differed significantly between groups (p < 0.001). Conclusions: In this study, CBCT was used to assess the morphology of the sella turcica. A majority of the subjects with cleft had a flattened sella turcica compared to that of the control group. A shorter length of the sella turcica was more evident in the cleft subjects than in the control group. (C) 2016 S. Karger AG, Basel