Which definition should be used to determine colchicine resistance among patients with familial Mediterranean fever?


Demir S.

Clinical and experimental rheumatology, cilt.36, sa.6, ss.97-102, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 6
  • Basım Tarihi: 2018
  • Dergi Adı: Clinical and experimental rheumatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.97-102
  • Anahtar Kelimeler: familial Mediterranean fever, colchicine resistance, colchicine unresponsiveness, RECOMMENDATIONS, ASSOCIATION, MANAGEMENT, DIAGNOSIS, ANAKINRA, CRITERIA, CHILDREN, SCORE, FMF
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objective. Colchicine is the main therapy for familial Mediterranean fever (FMF); however, 5-10% of patients are colchicine-resistant. There is no standard and validated definition for colchicine resistance. We aimed to compare the existing definitions for colchicine resistance in both adult and paediatric FMF patients to find out the best definition to determine colchicine-resistant patients.