Lantana montevidensis Essential Oil: Chemical Composition and Mosquito Repellent Activity against Aedes aegypti

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Blythe E. K., Tabanca N., DEMİRCİ B., Tsikolia M., Bloomquist J. R., Bernier U. R.

NATURAL PRODUCT COMMUNICATIONS, vol.11, no.11, pp.1713-1716, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 11
  • Publication Date: 2016
  • Doi Number: 10.1177/1934578x1601101122
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1713-1716
  • Eskisehir Osmangazi University Affiliated: No


The essential oil (EO) of Lantana montevidensis (Spreng.) Briq. (L. sellowiana Link & Otto) was investigated for its chemical composition and mosquito repellent activity. The essential oil obtained by hydrodistillation of aerial plant parts was analyzed by GC-FID and GC-MS. The major constituents were beta-elemene (22.0%), beta-caryophyllene (20.1%), and germacrene D (9.4%). Sesquiterpene hydrocarbons were present in considerable quantities (78.9%) in the L. montevidensis EO, followed by oxygenated sesquiterpenes (8.9%), monoterpene hydrocarbons (7.7%), oxygenated monoterpenes (1.9%), diterpenes (1.2%) and other compounds (0.2%). The oil of L. montevidensis was repellent with a minimum effective dosage (MED) of 0.021 +/- 0.013 mg/cm(2) as compared with that of the positive control N,N-diethyl-3-methylbenzamide (DEET) with a MED of 0.006 +/- 0.001 mg/cm(2)) against Aedes aegypti L. The major compound beta-elemene was tested individually for its repellency and had a MED value of 0.23 +/- 0.14 mg/cm(2) (DEET was 0.008 +/- 0.001 mg/cm(2)). This is the first report on the repellent activity of L. montevidensis EO and beta-elemene using human-based in vivo assays against Ae. aegypti.