In Vitro Protective Effect of Betaine on Peroxidative Injury Caused By Ethanol and Aspirin Exposure on Rat Brain Synaptosomes

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Sogut I., KANBAK G.

ERCIYES MEDICAL JOURNAL, cilt.38, sa.4, ss.144-148, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/etd.2016.0038
  • Dergi Adı: ERCIYES MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.144-148
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Aspirin intake of specific daily doses are advised by doctors to postmenapausal women and men above 40 years of age to prevent heart attack and even cancer in recent times. In vitro cytototoxic effects of different doses of ethanol (50 mM, 100 mM ve 200 mM) alone and together with 100 mu g/mL aspirin, and possible protective role of 1 mM betaine on rat brain synaptosomes were investigated.