In Vitro Protective Effect of Betaine on Peroxidative Injury Caused By Ethanol and Aspirin Exposure on Rat Brain Synaptosomes

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Sogut I., KANBAK G.

ERCIYES MEDICAL JOURNAL, vol.38, no.4, pp.144-148, 2016 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.5152/etd.2016.0038
  • Journal Name: ERCIYES MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.144-148
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Aspirin intake of specific daily doses are advised by doctors to postmenapausal women and men above 40 years of age to prevent heart attack and even cancer in recent times. In vitro cytototoxic effects of different doses of ethanol (50 mM, 100 mM ve 200 mM) alone and together with 100 mu g/mL aspirin, and possible protective role of 1 mM betaine on rat brain synaptosomes were investigated.