A novel wound healing ointment: A formulation of Hypericum perforatum oil and sage and oregano essential oils based on traditional Turkish knowledge


SÜNTAR İ., AKKOL E., KELEŞ H., Oktem A., BAŞER K. H. C. , YEŞİLADA E.

JOURNAL OF ETHNOPHARMACOLOGY, vol.134, no.1, pp.89-96, 2011 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 134 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jep.2010.11.061
  • Journal Name: JOURNAL OF ETHNOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.89-96

Abstract

Aim of the study: Hypericum perforatum L (Hypericaceae), olive oil (Oleaceae), Origanum Tourn ex L and Salvia L. species (Lamiaceae) are used against inflammatory disorders and for healing of skin wounds in traditional Turkish medicine. A new ointment formulation was developed to provide more efficient wound healing activity. The content of the formulation was as follows; olive oil extract of flowering aerial parts of Hypericum perforatum L, olive oil, an equivalent mixture of Origanum majorana L and Origanum minutiflorum Schwrd. et Davis essential oils (Origani aetheroleum), Salvia triloba L essential oil. The aim of the present study is to assess the wound healing potential of this new formulation by using in vivo and in vitro models as well as histopathological methods.