Peripheral Blood Regulatory T Cell Levels Are Correlated with Some Poor Prognostic Markers in Newly Diagnosed Lymphoma Patients


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GÜNDÜZ E., Sermet S., MUSMUL A.

CYTOMETRY PART B-CLINICAL CYTOMETRY, cilt.90, sa.5, ss.449-454, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 90 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/cyto.b.21330
  • Dergi Adı: CYTOMETRY PART B-CLINICAL CYTOMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.449-454
  • Anahtar Kelimeler: lymphoma, peripheral blood, regulatory T cells, flow cytometry, prognosis, FOLLICULAR LYMPHOMA, HIGH NUMBERS, SURVIVAL, IMPACT, FOXP3, MICROENVIRONMENT, LYMPHOCYTES, EXPRESSION, TREGS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Regulatory T cells (Tregs) are a specialized subpopulation of CD4+ T cells which maintain the immune system homeostasis. They may increase during cancer progression and have been correlated with a worse prognosis in many malignancies. However, the role of Treg cells in lymphoma is debated.