Peripheral Blood Regulatory T Cell Levels Are Correlated with Some Poor Prognostic Markers in Newly Diagnosed Lymphoma Patients

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GÜNDÜZ E., Sermet S., MUSMUL A.

CYTOMETRY PART B-CLINICAL CYTOMETRY, vol.90, no.5, pp.449-454, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 90 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1002/cyto.b.21330
  • Journal Name: CYTOMETRY PART B-CLINICAL CYTOMETRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.449-454
  • Keywords: lymphoma, peripheral blood, regulatory T cells, flow cytometry, prognosis, FOLLICULAR LYMPHOMA, HIGH NUMBERS, SURVIVAL, IMPACT, FOXP3, MICROENVIRONMENT, LYMPHOCYTES, EXPRESSION, TREGS
  • Open Archive Collection: AVESIS Open Access Collection
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: Regulatory T cells (Tregs) are a specialized subpopulation of CD4+ T cells which maintain the immune system homeostasis. They may increase during cancer progression and have been correlated with a worse prognosis in many malignancies. However, the role of Treg cells in lymphoma is debated.