Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against <i>Candida</i> spp.

Şen Kaya S., Kiraz N., Bariş A., Turan D., Öz Y., Dağ İ., ...More

Journal of medical microbiology, vol.70, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 70
  • Publication Date: 2021
  • Doi Number: 10.1099/jmm.0.001354
  • Journal Name: Journal of medical microbiology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Keywords: antifungal, calcineurin inhibitors, combination, synergistic interaction, IN-VITRO INTERACTIONS, TIME-KILL, CRYPTOCOCCUS-NEOFORMANS, FLUCONAZOLE, COMBINATION, ALBICANS, AGENTS, GLABRATA, CASPOFUNGIN, ANTAGONISM
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Introduction. The simultaneous use of antifungals with immunosuppressive agents has become a necessity for patients taking immunosuppressive therapy. However, antifungal drugs are problematic because of their limited target.