Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis


Beyazit Y., Sayilir A., Torun S., Suvak B., Yesil Y., Purnak T., ...More

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, vol.36, no.2, pp.162-168, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.clinre.2011.10.003
  • Title of Journal : CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
  • Page Numbers: pp.162-168

Abstract

Aim: Acute pancreatitis (AP) constitutes a systemic inflammatory process which is often accompanied by thrombosis and bleeding disorders. The role of platelets in the pathophysiology of the disease has not been elucidated yet. Mean platelet volume (MPV) is an index of platelet activation and reported to be influenced by inflammation. The objective of the present study is to assess whether platelet volume would be useful in predicting disease severity in AP. Additionally possible relationship of MPV with clinical and radiologic parameters in conjunction with other inflammatory markers during AP was also investigated.