Akademik Veri Yönetim Sistemi
DISABILITY AND REHABILITATION, 2024 (SCI-Expanded)
PurposeTo examine the effect of deep brain stimulation (DBS) on lower extremity dexterity in people with Parkinson's disease (PwPD) and to investigate the relationship between this effect and the effect of DBS on measures of different walking characteristics, and other features of Parkinson's disease.Materials and methodsThirty-six PwPD were included. Assessment was performed twice with DBS "on" and DBS "off" state.ResultsThe LEDT scores of both extremities, the Unified Parkinson Disease Rating Scale-motor section (UPDRS-III), the 10-Meter Walk Test (TMWT), the Timed Up and Go Test (TUG), the Figure-of-Eight Walk Test (FEWT), and the Three-Meter Backward Walk Test (TMBWT) scores were significantly better in "on" DBS condition than "off" DBS condition. The effect of DBS on lower extremity dexterity is related to age and levodopa equivalent daily dosage (LEDD). The effect of DBS on lower extremity dexterity and the effect of DBS on the bradykinesia, TUG, the FEWT, and the TMBWT were also related.ConclusionsDBS has a positive effect on lower extremity dexterity. Clinical characteristics such as age and LEDD and the effect of DBS on bradykinesia, walking with turning, curved walking, and backward walking is related with the effect of DBS on lower extremity dexterity. The age and levodopa equivalent daily dosage values of the patients should be considered when examining lower extremity dexterity in people with Parkinson's disease who have undergone deep brain stimulation (DBS).It may be beneficial to apply exercises to improve lower extremity dexterity for patients whose symptoms of bradykinesia do not progress as expected after DBS.Applying exercises to improve lower extremity dexterity may also be beneficial for patients who have complex walking deficits after DBS.