Nanostructured electrochemical cysteine sensor based on carbon nanotube supported Ru, Pd, and Pt catalysts

Kivrak H., Selçuk K., Er O. F., Aktaş N.

Materials Chemistry and Physics, cilt.267, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 267
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.matchemphys.2021.124689
  • Dergi Adı: Materials Chemistry and Physics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: Cysteine, Ru, Pd, Pt, Electrochemical, Amino acid sensor, FORMIC-ACID ELECTROOXIDATION, CARBOXYMETHYL-L-CYSTEINE, PEROXIDASE-LIKE ACTIVITY, SPECTROMETRIC DETERMINATION, COLORIMETRIC DETERMINATION, AU, NANOPARTICLES, ELECTRODE, PLATFORM, AG
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

© 2021 Elsevier B.V.At present, a voltammetric L-Cystein (Cys) sensor is developed based on carbon nanotube (MWCNT) supported Ru, Pd, and Pt monometallic catalyst modified glassy carbon electrodes (GCE). Ru/MWCNT, Pd/MWCNT, and Pt/MWCNT catalysts are prepared via sodium borohydride reduction method and characterized with advanced surface analytical techniques as inductively coupled plasma mass spectrometry (ICP-MS), N2 adsorption-desorption, X-ray diffraction (XRD), and transission electron microscopy (TEM). Characterization results reveal that these catalysts are succesfully sythesized at desired metal loadings. For electrochemical studies, GCE is modified with Ru/MWCNT, Pd/MWCNT, and Pt/MWCNT catalysts to obtain a disposable, inexpensive, and sensitive sensor for Cys. The electrochemical behavior of the modified GCE is investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Ru/MWCNT modified GCE electrode exhibits best Cys electro-oxidation activity and thus, further electrochemical studies as sensitivity and limit of detection determination, intereference study, and real sample analysis are performed on Ru/MWCNT modified GCE electrode. The Cys sensor has a linear response within the range of 0–200 μM with current sensitivity 0.3058 μA/μM (4307.05 μA/mMcm2), and 0.353 lowest detection limit at (S/N = 3) signal to noise ratio. Interference studies reveal that Ru/MWCNT modified GCE electrode is not affected by D-glucose, uric acid, L-Tyrosine, L-Trytophane, H2O2, homocysteine, and glutathione as common interfering species. The developed sensor based on Ru/MWCNT modified GCE electrode is also employed to quantify Cys in acetylcysteine drug sample. This novel study reports a strategy to sense Cys on Ru/MWCNT modified GCE electrode.