The effect of trimetazidine on liver regeneration after partial hepatectomy under hepatic blood inflow occlusion

Kaya Y., Coskun T., Aral E., Erkasap N., Var A.

HEPATO-GASTROENTEROLOGY, vol.50, no.51, pp.651-655, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 51
  • Publication Date: 2003
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.651-655
  • Keywords: hepatic blood, inflow occlusion, liver ischemia reperfusion, liver injury, liver regeneration, Trimetazidine, ISCHEMIA-REPERFUSION, REACTIVE OXYGEN, INJURY, INTERLEUKIN-6, MITOCHONDRIA, RATS
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background/Aims: It has been shown that hepatic blood inflow occlusion impairs liver regeneration. Our aim in this study was to investigate the effect of trimetazidine, known as an anti-ischemic and antioxidant agent, on liver regeneration after hepatic blood inflow occlusion.