CD105 (endoglin) expression as a prognostic marker of angiogenesis in squamous cell cervical cancer treated with radical radiotherapy

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Metcalfe E., Arık D., Öge T., Etiz D., Yalçın Ö. T., Kabukcuoglu S., ...More

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, vol.14, pp.1373-1378, 2018 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 14
• Publication Date: 2018
• Doi Number: 10.4103/0973-1482.203602
• Journal Name: JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1373-1378
• Keywords: Angiogenesis, CD105/endoglin, cervical cancer, chemoradiotherapy, radiotherapy, TUMOR ANGIOGENESIS, MICROVESSEL DENSITY, CHEMOTHERAPY, BIOMARKERS
• Eskisehir Osmangazi University Affiliated: Yes

Abstract

Introduction: Increased levels of endoglin may represent a new reagent of active neovascularization and angiogenesis process in various cancer types. The prognostic value of tumor CD105 (endoglin) expression in cervical squamous cell cancer (CSCC) patients treated with radical radiotherapy (RT) +/- chemotherapy was investigated.