Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors

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TEMEL H. E., ALTINTOP M. D., ÖZDEMİR A.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.15, no.3, pp.333-338, 2018 (ESCI, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 15 Issue: 3
• Publication Date: 2018
• Doi Number: 10.4274/tjps.20982
• Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.333-338
• Open Archive Collection: AVESIS Open Access Collection
• Eskisehir Osmangazi University Affiliated: No

Abstract

Objectives: In recent years, the design of anticholinesterase agents based on molecular hybridization of pharmacologically active scaffolds has attracted a great deal of interest in medicinal chemistry. For this purpose, we aimed to design and synthesize anticholinesterase agents based on the molecular hybridization of thiazole and pyrazoline scaffolds.