Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors

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TEMEL H. E., ALTINTOP M. D., ÖZDEMİR A.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.15, sa.3, ss.333-338, 2018 (ESCI, Scopus, TRDizin)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 15 Sayı: 3
• Basım Tarihi: 2018
• Doi Numarası: 10.4274/tjps.20982
• Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.333-338
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objectives: In recent years, the design of anticholinesterase agents based on molecular hybridization of pharmacologically active scaffolds has attracted a great deal of interest in medicinal chemistry. For this purpose, we aimed to design and synthesize anticholinesterase agents based on the molecular hybridization of thiazole and pyrazoline scaffolds.