Effect of home-based high-intensity interval training versus moderate-intensity continuous training in patients with myocardial infarction: a randomized controlled trial

YAKUT H., DURSUN H., Felekoğlu E., BAŞKURT A. A., Alpaydın A. Ö., ÖZALEVLİ S.

Irish Journal of Medical Science, vol.191, no.6, pp.2539-2548, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 191 Issue: 6
  • Publication Date: 2022
  • Doi Number: 10.1007/s11845-021-02867-x
  • Journal Name: Irish Journal of Medical Science
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.2539-2548
  • Keywords: Functional capacity, Health-related quality of life, High-intensity interval training, Home-based exercise, Myocardial infarction, QUALITY-OF-LIFE, OUTPATIENT CARDIAC REHABILITATION, OBSTRUCTIVE PULMONARY-DISEASE, AEROBIC CAPACITY, FUNCTIONAL-CAPACITY, MUSCLE STRENGTH, EXERCISE, PERFORMANCE, BENEFITS, IMPACT
  • Eskisehir Osmangazi University Affiliated: Yes


© 2021, The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.Background: Supervised high-intensity interval training (HIIT) has been proposed to be more effective than moderate-intensity continuous training (MICT) for improving exercise capacity, but there are not sufficient information effects of home-based HIIT and MICT in patients with myocardial infarction (MI). Aims: To compare the effects of home-based HIIT and MICT in patients with MI. Methods: Twenty-one patients with MI were randomly assigned to one of two home-based exercise modes: HIIT group and MICT group. Home-based HIIT and MICT were performed twice a week for 12 weeks with an exercise intensity of 85–95% of heart rate (HR) reserve and 70–75% HR reserve, respectively. The primary outcome measure was functional capacity. Secondary outcomes included resting blood pressure and HR, peripheral oxygen saturation, pulmonary function and respiratory muscle strength, dyspnea severity, body composition (body fat%, body mass ındex (BMI), fat free muscle), peripheral muscle strength, and health-related quality of life (HRQoL). Results: Functional capacity, measured by 6-minute walk test, increased in HIIT and MICT group (p < 0.05). Resting BP and HR, body fat%, and BMI were significantly decreased, and pulmonary functions, respiratory-peripheral muscle strength, and HRQoL were significantly increased in the both groups (p < 0.05). Home-based HIIT was more effective than MICT in improving pulmonary functions and lower extremity muscle strength (p < 0.05). Conclusions: This study suggests that HIIT and MICT can be applied at home-based in patients with MI and play an important role in improving functional capacity, health outcomes, and HRQoL. Trial registration: Clinical Trials Number: NCT04407624.