Perianal Paget’s Disease; Surgery and Non-surgical Interventions, Untreated Patient: a Report of Two Cases

Özdemir Ü., SALIŞ M., ÖZER İ., Ünal B.

Indian Journal of Surgery, vol.85, no.1, pp.169-174, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 85 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.1007/s12262-022-03376-6
  • Journal Name: Indian Journal of Surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, Veterinary Science Database
  • Page Numbers: pp.169-174
  • Keywords: Perianal Paget's disease, Extramammary Paget's disease, Perianal lesion, SURGICAL-TREATMENT, MAMMARY, MANAGEMENT, REGION, SKIN
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

© 2022, Association of Surgeons of India.Perianal Paget’s disease (PPD) is a rare intraepithelial adenocarcinoma. The clinical appearance of PPD may be confused with dermatitis and fungal infections of the skin, resulting in delayed diagnosis, sometimes for years. It may also be associated with secondary malignancies. Surgery and non-surgical methods such as radiotherapy, immunomodulating drugs, and chemotherapy are used in the treatment of PPD. In this case report, two patients with PPD are presented; the first was treated with surgical excision and radiotherapy and the second did not accept surgical or medical therapy. Although the lesion deepened and expanded towards adjacent structures, no secondary malignancy or metastasis was observed.