Perianal Paget’s Disease; Surgery and Non-surgical Interventions, Untreated Patient: a Report of Two Cases

Özdemir Ü., SALIŞ M., ÖZER İ., Ünal B.

Indian Journal of Surgery, cilt.85, sa.1, ss.169-174, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 85 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s12262-022-03376-6
  • Dergi Adı: Indian Journal of Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, Veterinary Science Database
  • Sayfa Sayıları: ss.169-174
  • Anahtar Kelimeler: Perianal Paget's disease, Extramammary Paget's disease, Perianal lesion, SURGICAL-TREATMENT, MAMMARY, MANAGEMENT, REGION, SKIN
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

© 2022, Association of Surgeons of India.Perianal Paget’s disease (PPD) is a rare intraepithelial adenocarcinoma. The clinical appearance of PPD may be confused with dermatitis and fungal infections of the skin, resulting in delayed diagnosis, sometimes for years. It may also be associated with secondary malignancies. Surgery and non-surgical methods such as radiotherapy, immunomodulating drugs, and chemotherapy are used in the treatment of PPD. In this case report, two patients with PPD are presented; the first was treated with surgical excision and radiotherapy and the second did not accept surgical or medical therapy. Although the lesion deepened and expanded towards adjacent structures, no secondary malignancy or metastasis was observed.