Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats

Kocak C., Kocak F. E., AKCILAR R., Isiklar Ö. Ö., Kocak H., Bayat Z., ...Daha Fazla

LIFE SCIENCES, cilt.147, ss.15-23, 2016 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 147
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.lfs.2016.01.038
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.15-23
  • Anahtar Kelimeler: Carnosic acid, Embelin, Heart, Isoproterenol, Myocardial infarction, Myocardial ischemia, ISCHEMIA-REPERFUSION INJURY, DECREASES CARDIOMYOCYTE APOPTOSIS, CULTURED CARDIAC MYOCYTES, OXIDATIVE STRESS, INDUCED CARDIOTOXICITY, ANTIOXIDANT RESPONSE, BINDING PROTEIN, TROPONIN-I, DAMAGE, HEART
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Aims: Acute myocardial infarction is a serious acute cardiac disorder and heart disease is still a major public health problem in adults. We investigated the effects of embelin (EMB) and carnosic acid (CA) in animals with isoproterenol (ISO)-induced myocardial injury.