SEROPOSITIVITY OF CONGENITAL TOXOPLASMOSIS IN TURKEY, COMPARISON OF RESULTS WITH WORLD LITERATURES

Doğan N.

13th World Congress of the World Society for Pediatric Infectious Diseases (WSPID 2023), Durban, Güney Afrika, 14 - 17 Kasım 2023,, Durban, Güney Afrika, 14 - 17 Kasım 2023, ss.321-322, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Durban
  • Basıldığı Ülke: Güney Afrika
  • Sayfa Sayıları: ss.321-322
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

EP107 / #604 Topic: AS14 Public Health and Epidemiology: / AS14c Healthcare-associated infections SEROPOSITIVITY OF CONGENITAL TOXOPLASMOSIS IN TURKEY, COMPARISON OF RESULTS WITH WORLD LITERATURES Nihal Dogan Eskisehir Osmangazi University, Microbiology/parasitology, Eskisehir, Turkey Background: Toxoplasmosis is an opportunistic protozoan disease caused by Toxoplasma gondii (T. gondii) infection. Morbidity and mortality are high in neonates and immunocompromised patients. Aims: Data from newborn and childhood are generally scarce. Anti Toxoplasma gondii antibody results in infants born with congenital risk in our laboratory in the last five years were evaluated together with similar studies conducted in Turkey and in the world. Methods: Anti Toxo ELISA IgG/IgM and avidity test results were evaluated in newborn sera sent to ESOGU Medical Faculty Microbiology laboratory with a preliminary diagnosis of congenital Toxoplasmosis between 2018-2022. Data on congenital toxoplasmosis performed in Turkey and in the world were searched in PubMed and Google schoolar data. Results: Toxoplasmosis during pregnancy can cause congenital toxoplasmosis with a rate of 1-30%. In case of maternal infection, fetal infection should be investigated. Intracranial sequelae are mostly reported despite treatment. Seroprevalence in women with seroprevalence is between 10-30% in Turkey and Europe. In the USA, it has been reported to be 01.5 per cent. It is estimated that transmission is higher in rural areas, but there are not sufficient data. According to the National Microbiology Standards in Turkey, if Toxoplasma IgG and/or IgM positivity is detected, it is recommended to repeat the tests at 2-3 week intervals and to utilise avidity, SFDT and molecular methods. Conclusions: Although the rates have decreased in the USA and Europe thanks to effective control strategies in recent years, it is still an important in developing countries.