Vascular endothelial growth factor-2578 A/C,-460 T/C and+405 G/C polymorphisms in polycystic ovary syndrome

VURAL, Pervin; Kusku-Kiraz, ZEYNEP; Dogru-Abbasoglu, Semra; Cil, Esra; Karadag, Berrin; Akgul, Cemil; Uysal, Muejdat

doi:10.1016/j.ejogrb.2009.06.026

Vascular endothelial growth factor-2578 A/C,-460 T/C and+405 G/C polymorphisms in polycystic ovary syndrome

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VURAL P., Kusku-Kiraz Z., Dogru-Abbasoglu S., Cil E., Karadag B., Akgul C., ...More

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.147, no.1, pp.57-60, 2009 (SCI-Expanded)

Publication Type: Article / Article
Volume: 147 Issue: 1
Publication Date: 2009
Doi Number: 10.1016/j.ejogrb.2009.06.026
Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.57-60
Keywords: Polycystic ovary syndrome, Vascular endothelial growth factor, Polymorphism, FACTOR GENE POLYMORPHISMS, STROMAL BLOOD-FLOW, PERMEABILITY FACTOR, HYPERSTIMULATION SYNDROME, VEGF GENE, ASSOCIATION, WOMEN, SUSCEPTIBILITY, EXPRESSION, GRANULOSA
Eskisehir Osmangazi University Affiliated: No

Abstract

Objective: Vascular endothelial growth factor (VEGF) may be involved in the physiological regulation of ovarian angiogenesis and pathogenesis of polycystic ovary syndrome (PCOS). VEGF -2578 A/C, -460 T/C and +405 G/C single nucleotide polymorphisms (SNPs) are known to be related to VEGF production.