IL-15 Gene Polymorphism in Celiac Disease Patients and Their Siblings
TURKISH JOURNAL OF GASTROENTEROLOGY, vol.32, no.4, pp.349-356, 2021 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 32 Issue: 4
- Publication Date: 2021
- Doi Number: 10.5152/tjg.2021.19083
- Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
- Page Numbers: pp.349-356
- Keywords: Celiac disease, IL-15, gene polymorphism, RHEUMATOID-ARTHRITIS, TURKISH CHILDREN, ASSOCIATION
- Eskisehir Osmangazi University Affiliated: Yes
Abstract
Background: Celiac disease (CD) is an immune-mediated enteropathy characterized by lifelong gluten intolerance. lnterleukin-15 (IL-15) is a proinflammatory cytokine that is considered a key component in the immune reaction triggered by gluten. Our aim of this study was to evaluate the influence of IL-15 gene polymorphisms on CD development and clinical presentation.