IL-15 Gene Polymorphism in Celiac Disease Patients and Their Siblings
TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.32, sa.4, ss.349-356, 2021 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.5152/tjg.2021.19083
- Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.349-356
- Anahtar Kelimeler: Celiac disease, IL-15, gene polymorphism, RHEUMATOID-ARTHRITIS, TURKISH CHILDREN, ASSOCIATION
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Background: Celiac disease (CD) is an immune-mediated enteropathy characterized by lifelong gluten intolerance. lnterleukin-15 (IL-15) is a proinflammatory cytokine that is considered a key component in the immune reaction triggered by gluten. Our aim of this study was to evaluate the influence of IL-15 gene polymorphisms on CD development and clinical presentation.