IL-15 Gene Polymorphism in Celiac Disease Patients and Their Siblings

Kara Y., Eren M., Arslan S., Çilingir O.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.32, sa.4, ss.349-356, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/tjg.2021.19083
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.349-356
  • Anahtar Kelimeler: Celiac disease, IL-15, gene polymorphism, RHEUMATOID-ARTHRITIS, TURKISH CHILDREN, ASSOCIATION
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Celiac disease (CD) is an immune-mediated enteropathy characterized by lifelong gluten intolerance. lnterleukin-15 (IL-15) is a proinflammatory cytokine that is considered a key component in the immune reaction triggered by gluten. Our aim of this study was to evaluate the influence of IL-15 gene polymorphisms on CD development and clinical presentation.