Akademik Veri Yönetim Sistemi
Indian Journal of Surgery, 2025 (SCI-Expanded)
Pancreatic cancer is characterized by one of the highest mortality rates among all gastrointestinal malignancies. Surgical treatment is the most effective option when diagnosed in the early stages; however, postoperative prognosis varies considerably based on patients’ clinical and biochemical characteristics. To aid in prognosis, several indices have been developed. The CALLY index, which combines lymphocyte count, albumin levels, and C-reactive protein (CRP) levels, aims to evaluate patient prognosis. This study evaluates the capability of the CALLY index in predicting mortality in patients undergoing curative surgery for pancreatic cancer, and compares its predictive value with lymphocyte-CRP ratio (LCR) and prognostic nutritional index (PNI). The study comprised 121 patients who had undergone curative surgery for pancreatic cancer. Preoperative blood samples were utilized to calculate the CALLY, LCR, and PNI values,which were subsequently compared to assess their predictive significance for mortality. Furthermore, the study examined the association between the CALLY index and demographic data, clinicopathological features, and early postoperative complications. The CALLY index demonstrated the highest predictive value for mortality (p < 0.05) in all periods. Moreover, the CALLY index was notably reduced in patients who experienced early postoperative complications. The CALLY index appears to be a valuable tool for predicting mortality in cases undergoing curative operative management for pancreatic cancer. Our study demonstrates that the CALLY index provides stronger predictive power compared to other prognostic indices. This suggests that the integration of the CALLY index into clinical practice could offer meaningful support in assessing and managing patient prognosis.