Effects of Conivaptan versus Mannitol on Post-Ischemic Brain Injury and Edema

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CAN B., ÖZ S., ŞAHİNTÜRK V., MUSMUL A., ALATAŞ İ. Ö.

EURASIAN JOURNAL OF MEDICINE, vol.51, no.1, pp.42-48, 2019 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5152/eurasianjmed.2019.18368
  • Journal Name: EURASIAN JOURNAL OF MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.42-48
  • Keywords: Brain injury, conivaptan, ischemia-reperfusion, mannitol, neuronal damage, ISCHEMIC-STROKE, ARGININE-VASOPRESSIN, RECEPTOR ANTAGONIST, FOREBRAIN ISCHEMIA, NEUROPROTECTION, OCCLUSION, RAT
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: The aim of this study was to compare the effects of conivaptan, an arginine vasopressin antagonist, and mannitol, a sugar alcohol, on cerebral ischemia-induced brain injury and edema in rats.