Correlation of Indeterminate Lesions of COVID-19 Pneumonia Detected on Computed Tomography with RT-PCR Results


Aydin N., Cihan Ç., Us T., Öz Y., Oztunali Ç., Yılmaz Ş., ...Daha Fazla

CURRENT MEDICAL IMAGING, cilt.18, sa.8, ss.862-868, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.2174/1573405618666220111095357
  • Dergi Adı: CURRENT MEDICAL IMAGING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.862-868
  • Anahtar Kelimeler: COVID-19 pneumonia, indeterminate lesions, computed tomography, SARS-CoV-2, RT-PCR, GGOs, CORONAVIRUS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: The typical findings of COVID-19 pneumonia include multilobar ground- glass opacities and consolidation areas observed predominantly in the basal and peripheral parts of both lungs in computed tomography. Objective: The current study aimed to correlate indeterminate lesions of COVID-19 pneumonia detected on computed tomography with the results of the reverse transcription-polymerase chain reaction (RT-PCR) test. Methods: Patients with high-resolution computed tomography images that were reported to contain indeterminate lesions in terms of COVID-19 pneumonia were included retrospectively in the study. The lesions were categorized and the patterns were classified. The RT-PCR-positive and the RT-PCR-negative patients were compared. PResults: The RT-PCR-positive patients exhibited a higher rate of peripheral lesions. Limited consolidation areas were not detected in the RT-PCR-positive patients. In the RT-PCR-negative patients, the rates of acinar nodules and the tree-in-bud pattern were significantly higher. The RT-PCR-negative patients had higher nodular contour features and lesion coalescence. In the subgroup consisting of lesions with ground-glass opacities and/or ground-glass opacity around the nodule, the rate of nodular contour positivity was significantly higher in the RT-PCR- positive patients. Conclusion: COVID-19 pneumonia should be suspected when peripheral indeterminate lesions are detected. When indeterminate lesions, such as tree-in-bud pattern, acinar nodules and limited consolidation area are detected, alternative diagnoses should be considered first, even if there are ground glass opacities accompanying these lesions.