Cellular Trace Element Changes in Type 1 Diabetes Patients

Ugurlu V., Binay C., ŞİMŞEK E., BAL C.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.8, no.2, pp.180-186, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.4274/jcrpe.2449
  • Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.180-186
  • Keywords: Type 1 diabetes mellitus, trace elements, magnesium tolerance test, MAGNESIUM-DEFICIENCY, CHILDREN, ZINC, HYPOMAGNESEMIA, MELLITUS, COPPER, LEVEL, SERUM, ADOLESCENTS, RETINA
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Type 1 diabetes mellitus (T1DM) may lead to deficiencies in trace elements that have substantial functions in the human organism. Changes in serum magnesium (Mg), copper (Cu), and zinc (Zn) levels are correlated with metabolic control and diabetes complications. The aim of this study was to evaluate the intra-erythrocyte levels of trace elements and urinary Mg excretion following intravenous (iv) Mg tolerance testing in children with T1DM.