Akathisia in association with herpes simplex encephalitis relapse and opercular syndrome in children

Kocak O., YARAR C., Yakut A., Ekici A., Yimenicioglu S., ŞAYLISOY S.

BRAIN & DEVELOPMENT, vol.36, no.2, pp.167-170, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.1016/j.braindev.2013.02.007
  • Journal Name: BRAIN & DEVELOPMENT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.167-170
  • Eskisehir Osmangazi University Affiliated: Yes


We report a 2-year-old boy with herpes simplex virus type 1 encephalitis (HSE) and opercular syndrome who presented with clinical relapse characterized by chorea-like involuntary movements that suggest akathisia. The patient initially presented with multiple focal seizures that cause epilepsia partialis continua, polymerase chain reaction (PCR) for herpes simplex virus type 1 was positive. He developed hypersalivation, speech and swallowing difficulties within 30 days. Based on these findings the patient was diagnosed as having opercular syndrome due to HSE. He developed akathisia on 44th day of admission as a relapse and he was successfully treated with propranolol.