The Relationship between Insulin Resistance and Liver Damage in non-alcoholic Fatty Liver Patients

Cetin E. G., DEMİR N., Sen I.

MEDICAL BULLETIN OF SISLI ETFAL HOSPITAL, cilt.54, sa.4, ss.411-415, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.14744/semb.2018.83604
  • Dergi Adı: MEDICAL BULLETIN OF SISLI ETFAL HOSPITAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.411-415
  • Anahtar Kelimeler: HOMA-IR, insulin resistance, Non-alcoholic fatty liver, INDEPENDENT PREDICTORS, METABOLIC SYNDROME, RISK-FACTORS, DISEASE, FIBROSIS, MORTALITY, NAFLD
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objectives: Non-alcoholic fatty liver disease (NAFLD) is closely associated with diseases, such as obesity, diabetes mellitus, metabolic syndrome, which are characterized by insulin resistance. NAFLD is thought to be a manifestation of metabolic syndrome in the liver. Liver fibrosis has a high prognostic significance in non-alcoholic steatohepatitis (NASH). In this study, the relationship between insulin resistance and the histopathological changes in the liver was investigated in biopsy-proven NAFLD patients.