The Relationship between Insulin Resistance and Liver Damage in non-alcoholic Fatty Liver Patients

Cetin E. G., DEMİR N., Sen I.

MEDICAL BULLETIN OF SISLI ETFAL HOSPITAL, vol.54, no.4, pp.411-415, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.14744/semb.2018.83604
  • Journal Name: MEDICAL BULLETIN OF SISLI ETFAL HOSPITAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.411-415
  • Keywords: HOMA-IR, insulin resistance, Non-alcoholic fatty liver, INDEPENDENT PREDICTORS, METABOLIC SYNDROME, RISK-FACTORS, DISEASE, FIBROSIS, MORTALITY, NAFLD
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objectives: Non-alcoholic fatty liver disease (NAFLD) is closely associated with diseases, such as obesity, diabetes mellitus, metabolic syndrome, which are characterized by insulin resistance. NAFLD is thought to be a manifestation of metabolic syndrome in the liver. Liver fibrosis has a high prognostic significance in non-alcoholic steatohepatitis (NASH). In this study, the relationship between insulin resistance and the histopathological changes in the liver was investigated in biopsy-proven NAFLD patients.