Severe consumptive hypothyroidism caused by multiple infantile hepatic haemangiomas

ŞİMŞEK E., Demiral M., Gundogdu E.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.31, sa.7, ss.823-827, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1515/jpem-2018-0055
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.823-827
  • Anahtar Kelimeler: consumptive hypothyroidism, infantile hepatic haemangioma, type 3 iodothyronine deiodinase., TYPE-3 IODOTHYRONINE DEIODINASE
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Infantile hepatic haemangiomas (IHHs) produce an excess of the thyroid hormone inactivating enzyme type-3 iodothyronine deiodinase (D3), leading to rapid degradation of thyroid hormones and consum-ptive hypothyroidism. The L-thyroxine replacement dose in patients with consumptive hypothyroidism is inappropriately higher than that in congenital hypothyroidism.