JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, vol.31, no.7, pp.823-827, 2018 (SCI-Expanded)
Background: Infantile hepatic haemangiomas (IHHs) produce an excess of the thyroid hormone inactivating enzyme type-3 iodothyronine deiodinase (D3), leading to rapid degradation of thyroid hormones and consum-ptive hypothyroidism. The L-thyroxine replacement dose in patients with consumptive hypothyroidism is inappropriately higher than that in congenital hypothyroidism.