Cytomegalovirus DNAemia Detected with Real-Time Polymerase Chain Reaction in Hematopoietic Stem Cell Transplant Patients

Sahin D. G., GÜNDÜZ E., KAŞİFOĞLU N., Akay O. M., US T., Gulbas Z.

ADVANCES IN THERAPY, cilt.30, sa.8, ss.784-791, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s12325-013-0049-9
  • Dergi Adı: ADVANCES IN THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.784-791
  • Anahtar Kelimeler: CMV DNAemia, Hematopoietic stem cell transplantation, Pre-emptive therapy, Real-time polymerase chain reaction, BONE-MARROW-TRANSPLANTATION, PP65 ANTIGENEMIA ASSAY, PERIPHERAL-BLOOD, CMV INFECTION, RISK-FACTORS, DISEASE, RECIPIENTS, PCR, SURVEILLANCE, REACTIVATION
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Cytomegalovirus (CMV) infections continue to cause significant morbidity and mortality in hematopoietic stem cell transplant (HSCT) recipients. Successful pre-emptive therapy in transplant patients depends on the availability of reliable diagnostic tests for CMV infections. The purpose of this retrospective study was to evaluate CMV DNA viral load, incidence of CMV disease and CMV seropositivity, risk factors and correlation between CMV DNA positivity and clinical course in HSCT patients.