Cytomegalovirus DNAemia Detected with Real-Time Polymerase Chain Reaction in Hematopoietic Stem Cell Transplant Patients


Sahin D. G., GÜNDÜZ E., KAŞİFOĞLU N., Akay O. M., US T., Gulbas Z.

ADVANCES IN THERAPY, vol.30, no.8, pp.784-791, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.1007/s12325-013-0049-9
  • Journal Name: ADVANCES IN THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.784-791
  • Keywords: CMV DNAemia, Hematopoietic stem cell transplantation, Pre-emptive therapy, Real-time polymerase chain reaction, BONE-MARROW-TRANSPLANTATION, PP65 ANTIGENEMIA ASSAY, PERIPHERAL-BLOOD, CMV INFECTION, RISK-FACTORS, DISEASE, RECIPIENTS, PCR, SURVEILLANCE, REACTIVATION
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Cytomegalovirus (CMV) infections continue to cause significant morbidity and mortality in hematopoietic stem cell transplant (HSCT) recipients. Successful pre-emptive therapy in transplant patients depends on the availability of reliable diagnostic tests for CMV infections. The purpose of this retrospective study was to evaluate CMV DNA viral load, incidence of CMV disease and CMV seropositivity, risk factors and correlation between CMV DNA positivity and clinical course in HSCT patients.