Smell impairment in patients with chronic rhinosinusitis: a real-life study

Passali G. C., Passali D., CİNGİ C., Ciprandi G.

European Archives of Oto-Rhino-Laryngology, cilt.279, sa.2, ss.773-777, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 279 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1007/s00405-021-06848-9
  • Dergi Adı: European Archives of Oto-Rhino-Laryngology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.773-777
  • Anahtar Kelimeler: Chronic rhinosinusitis, Nasal polyps, Olfactory dysfunction, Real-life setting, Biologics, NASAL POLYPS, ODOR DISCRIMINATION, IDENTIFICATION, DYSFUNCTION, QUALITY
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Objective: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a frequently occurring condition involving type 2 inflammation. It has a global prevalence of approximately 4% and has a major effect on the quality of life of those affected by it. CRSwNP is a complex condition for otorhinolaryngologists to manage, since its precise pathogenic basis has not been established, treatment is challenging and the condition often recurs. It is common to find abnormalities in smelling in those with CRSwNP. Materials and methods: This cross-sectional study enrolled patients suffering from CRS. Three groups were compared: 1812 patients with CRS, 571 with CRSwNP, and 120 with CRSwNP treated by FESS. The Sniffin’ Sticks® olfactory test was used to measure olfactory function in all patients. Results: Olfactory dysfunction was a common symptom in patients with CRS, ranging in frequency from 56 to 74%. In patients with CRSwNP, impairment of sense of smell affected 64% of subjects (42% with anosmia, 10% with hyposmia, and 12% with cacosmia). After surgery, there was a significant improvement in the ability to smell normally. Conclusion: The present study confirms that impairment of smell is a common symptom in patients with chronic rhinosinusitis, mainly in subjects with nasal polyps. FESS reduces the prevalence of olfactory dysfunction.