Urological manifestations of the Wolfram syndrome: Observations in 14 patients

Tekgul S., Oge O., Simsek E. , Yordam N., Kendi S.

JOURNAL OF UROLOGY, cilt.161, sa.2, ss.616-617, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 161 Konu: 2
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0022-5347(01)61982-7
  • Sayfa Sayıları: ss.616-617


Purpose: Since the initial description of the Wolfram syndrome, various anomalies have been associated with this rare entity. Urinary tract dilatation and bladder dysfunction, usually in the form of a large, atonic bladder, are coexisting features of this syndrome that are commonly believed to be secondary to high urine output in diabetes insipidus, The presentation and nature of the urological manifestations of this syndrome remain controversial due to the lack of large series in the literature. We evaluated the urological manifestations of this rare syndrome. To our knowledge we report the largest series of patients (14) with the Wolfram syndrome who underwent a complete urological evaluation.