Comparison of the efficacy and safety of topical clindamycin and 5% benzoyl peroxide with nadifloxacin cream and 5% benzoyl peroxide gel in the treatment of acne vulgaris and assessment of the effects of these treatments on quality of life

Kirkagac A., SARAÇOĞLU Z. N., Aksu A. E. K.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, vol.49, no.1, pp.54-59, 2015 (ESCI) identifier identifier


Background and Design: Acne vulgaris is a multifactorial chronic inflammatory disease of the pilosebaceous unit. Topical antibiotics and anti-inflammatory treatment are used for mild to moderate acne. Clindamycin is frequently used for acne treatment, although nadifloxacin is a relatively new agent. There are few studies evaluating the efficacy of nadifloxacin. Its effectiveness in improving quality of life has not been determined previously. In this study, it is aimed to compare the efficacy of these two agents, and to evaluate the effect of these treatments on quality of life.