Protective effect of leptin against ischemia-reperfusion injury in the rat small intestine

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Hacioglu A., Algin C., Pasaoglu O., Pasaoglu E., Kanbak G.

BMC GASTROENTEROLOGY, cilt.5, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1186/1471-230x-5-37
  • Dergi Adı: BMC GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: The small intestine is extremely sensitive to ischemia-reperfusion (I/R) injury and a range of microcirculatory disturbances which contribute to tissue damage. Previous studies have shown that leptin plays an important physiological role in the microvasculature. The aim of this study was to evaluate the protective effects of leptin in I/R - induced mucosal injury in the small intestine.