Cutaneous leiomyomas are rare benign tumors arising from smooth muscle cells. The combination of cutaneous leiomyomatosis, uterine leiomyomatosis and renal cell cancer is referred to as "multiple cutaneous and Uterine Leiomyomatosis syndrome (Reed's syndrome)". A forty-five-year-old female patient was admitted to our clinic with multiple painful bumps on the body. Diabetes mellitus and hysterectomy operation due to leiomyoma were present in her past medical history. Dermatologic examination revealed multiple, painful, skin coloured-red papulonodules forming clusters on the bilateral lumbar region and a few lesions on the right arm and back. Histopathological examination of the biopsy specimen revealed leiomyoma. Gabapentin therapy was initiated and in the one-month follow-up, it was observed that she had relief from pain.