Serum dipeptidyl peptidase-IV: A better screening test for early detection of mucopolysaccharidosis?


Kurt I., Sertoglu E., OKUR İ., Tapan S., Uyanik M., KAYADİBİ H., ...Daha Fazla

CLINICA CHIMICA ACTA, cilt.431, ss.250-254, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 431
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.cca.2014.02.012
  • Dergi Adı: CLINICA CHIMICA ACTA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.250-254
  • Anahtar Kelimeler: Mucopolysaccharidoses, Urinary GAG/Creatinine ratio, Serum DPP-IV enzyme activity, LYSOSOMAL STORAGE DISORDERS, ADENOSINE-DEAMINASE, DIMETHYLMETHYLENE BLUE, PLASMA CHITOTRIOSIDASE, URINE SAMPLES, DIAGNOSIS, GLYCOSAMINOGLYCANS, PROTEINS, DISEASES, CD26
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

We aimed to investigate the diagnostic utility of serum DPP-IV enzyme activity, urinary GAG/Cre ratio, chitotriosidase activity, total adenosine deaminase (ADA) and ADA-1 isoenzyme activity in the diagnosis of MPS. 31 MPS patients which were previously diagnosed by clinical and enzymatic analysis and 31 healthy controls matched with age and gender were included in this study.