Calciphylaxis in a patient with rheumatoid arthritis without renal failure and hyperparathyroidism: The possible role of long-term steroid use and protein S deficiency

Korkmaz C., Dundar E., Zubaroglu I.

CLINICAL RHEUMATOLOGY, vol.21, no.1, pp.66-69, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1007/s100670200016
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.66-69
  • Keywords: calciphylaxis, protein S deficiency, rheumatoid arthritis, steroid use, HEMODIALYSIS PATIENT, NECROSIS, PARATHYROIDECTOMY, DIALYSIS, DISEASE
  • Eskisehir Osmangazi University Affiliated: Yes


Calciphylaxis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to small and medium-sized vessel calcification that is seen almost exclusively in patients with end-stage renal disease and hyperparathyroidism. We report a case of calciphylaxis that may very well be due to a long-term steroid use in a rheumatoid arthritis patient who had neither end-stage renal disease nor hyperparathyroidism. We also discuss the possible role of protein S deficiency as a contributing factor.