The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia//reperfusion induced rats

Erkasap, S.; ERKASAP, NİLÜFER; Bradford, B.; Mamedova, L.; UYSAL, ONUR; Ozkurt, METE; Ozkurt, R.; Kutlay, O.; Bayram, B.

doi:10.4149/bll_2017_086

The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia//reperfusion induced rats

Copy For Citation

Erkasap S., ERKASAP N., Bradford B., Mamedova L., UYSAL O., Ozkurt M., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.118, no.8, pp.443-448, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 118 Issue: 8
Publication Date: 2017
Doi Number: 10.4149/bll_2017_086
Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.443-448
Keywords: leptin, resveratrol, TNF-alpha, caspase 3, apoptosis, JAK-STAT PATHWAY, NF-KAPPA-B, ISCHEMIA/REPERFUSION INJURY, TNF-ALPHA, MYOCARDIAL ISCHEMIA/REPERFUSION, ISCHEMIA, CARDIOPROTECTION, PROTECTION, APOPTOSIS, FAILURE
Eskisehir Osmangazi University Affiliated: Yes

Abstract

OBJECTIVE: Our study aimed to investigate the possible modifying effects of leptin and combined use of resveratrol on rat renal I/R injury and their relationship on signal pathways and apoptosis-related mechanisms.